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At ADLADICS, we recognize that current laboratory testing is falling short of the needs of our patients. With a focus on blood counts and serum chemistries, getting “lab work” done today is not giving us the answers that we need to identify and treat the major causes of illness and death.

Our Test will be:

  • NON-INVASIVE - urine samples, not painful blood sticks.

  • COMPREHENSIVE - one test, not hundreds of different and expensive ones.

  • ACCURATE - based on epigenetic changes, not counts and chemistry levels.

  • INTELLIGENT - based on reproducible algorithms, computer learning and artificial intelligence analysis of massive amount of epigenetic data.

  • RELEVANT - focused on what hurts us: cancer, infection, cardiovascular and neurodegenerative disease, and currently misunderstood syndromes for which diagnosis is currently difficult.

Our Aims

 

Improve Sample Collection.

Getting lab work done doesn’t have to be painful. Everyday our kidneys filter the entirety of our blood volume over 40 times a day. That filtrate is excreted in urine. In that urine are millions of tiny DNA fragments called cfDNA. We are identifying the optimal, hassle-free collection technique for urine, and then stabilizing and extracting that cfDNA from that urine.

Improve Sample Processing.

In different disease states and in different tissues, patterns of DNA methylation change. These DNA methylation changes in cfDNA can be identified and quantified through a process called bisulfite conversion. Using next generation sequencing, abnormal patterns of DNA methylation can be used to identify current disease and risk factors for developing disease in the future.

 

Improve Sample Analysis.

Researchers around the world are working to identify specific epigenetic changes in cfDNA that indicates disease. We are aggregating this data and by using both artificial intelligence and machine learning, we are identifying which cfDNA comes from with tissues within the body and specific patterns within those tissues that signify disease. Best of all, one sample can be used to test for virtually all disease processes.

Improve Results for patients.

An unfortunate characteristic of “lab work” today is that it is reported in such a way that most patients have little understanding of what they mean. In fact, most people believe that current testing is much better than it actually is. We are working to insure that results released from ADLADICS are clearly understood and actionable so that results are reported as they should be - with the patient in mind.